Preparation of Acetylsalicylic Acid (Aspirin)
Aspirin is a salicylate drug and it is ordinarily known as a painkiller and infamously know for when it has been in excess causing stomach ulcers to adults and even have a possibility of being lethal to children. It was synthesized for the first time in 1853, by a scientist named Charles Frédéric Gerhardt however it was yet until 1897 a company named Bayer began investigating its use as a medicine and aspirin went on sale in 1899. In scientific nomenclature it is also known as acetylsalicylic mordant, mainly as it is derived from salicylic acid with the addition of acetic anhydride. The harvest-home is mainly used to treat migraines, where the patient usually takes 2 tablets of 325 mg content of acetylsalicylic acid. However it is also used in the prevention of blood clots, strokes and heart attacks. The reason being that it has the moment of an antiplatelet and therefore inhibits thromboxane production, which creates patches covering damaged blood vessel walls, where tablets usually are given with 81 mg content of acetylsalicylic acid.
The pastime is the proposed mechanism for the preparation of acetylsalicylic acid (aspirin), where the catalyst is sulfuric acid providing a proton during the reaction:
There are several galosh hazards and precautions during the experiment that should be informed to anyone who has not performed the procedure at any earlier occasion. For each compound there whitethorn be various risks to ones health upon exposure. These admit:
Salicylic acid: pestiferous when in contact with skin, by ingestion/ingestion and can be irritant. It can harm a human fetus, and cause mutagenic effects as healthful as sensitizing effects upon repeated exposure. Wear commensurate gloves and eye protection.
Acetic anhydride: Flammable, avoid oxidizing agents. It is poisonous, corrosive and causes severe burns. Harmful if swallowed/inhaled or in contact with eyes, can cause smashed respiratory irritation. Wear suitable gloves and...If you want to get a full essay, order it on our website: Orderessay
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